The Effectiveness of Preemptive Nebulized Dexamethasone in Reducing Post-Operative Sore Throat in… (NCT04771026) | Clinical Trial Compass
CompletedNot Applicable
The Effectiveness of Preemptive Nebulized Dexamethasone in Reducing Post-Operative Sore Throat in Supraglottic Airway
Malaysia140 participantsStarted 2020-12-01
Plain-language summary
This study aims to study the effectiveness of preoperatively nebulized dexamethasone in reducing the incidence and severity of Post Operative Sore Throat, POST in patients undergoing surgery under general anesthesia using the Ambu® AuraGainTM SGA device, with secondary aims of determining the effectiveness of dexamethasone in reducing post-operative cough severity and hoarseness of voice
Who can participate
Age range
18 Years – 70 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Between the ages of 18-70 years
* American Society of Anaesthesiology (ASA) physical status of 1 and 2
* Patients undergoing elective procedures under general anaesthesia between the data collection period suitable for SGA device
Exclusion Criteria:
* Pre-existing sore throat/hoarseness on pre-operative assessment
* Patients with history of postoperative nausea or vomiting
* Recent (2 weeks) upper or lower respiratory tract infection
* Known hypersensitivity to dexamethasone or on regular steroids
* Uncontrolled diabetes of capillary blood sugar more than 10mmol/l on pre-operative assessment
* Morbidly obese with BMI \> 40 kg/m2
* Procedure exceeding 3 hours duration
* Procedure requiring prone or Trendelenburg position or manipulation of head post-induction
* Oral and neck surgeries
* Pregnant patients
* Patients with cognitive disabilities
* Patients requiring nasogastric tube or nasal temperature probe insertion
* Patient refusal
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Incidence of POST up to 24 hours post-operatively in patients who received pre-operative nebulized dexamethasone