The present study explored the effects of the implementation of the Pythagorean Self Awareness Intervention (PSAI) on the dynamics of stress-related aging factors of immune cells in healthy volunteers and a cohort patients with type 2 diabetes mellitus . The primary aim was to evaluate the effectiveness of PSAI on two key biomarkers of biological age, telomere length and proteasome levels, indicative of the crosstalk between cellular oxidative status and replicative potential, with respect to metabolic, hormonal and mental status changes. Secondary aims of this study included reduction of depression, perceived stress, anxiety and the establishment of lifestyle changes to enhance the quality of everyday life, including better quality of sleep, eating behaviours and an overall healthier status.
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Determination of telomeres' length
Timeframe: 2 months
Determination of telomeres' length
Timeframe: 6 months
Determination of 20S proteasome concentration
Timeframe: 6 months
Healthy Lifestyle and Personal Control Questionnaire
Timeframe: 6 months
Glycosylated haemoglobin
Timeframe: 6 months