Root Canal Obturation With a Ready-to-use Root Canal Sealer (PA1704) Versus BioRoot™ RCS: a Randomized Controlled Trial

Inclusion Criteria: * Adult male or female (age ≥ 18 years) * Patient requiring a primary or a secondary root canal obturation on a single or multi-rooted tooth, * Patient geographically stable who can be followed by the same investigator site for 2 years, * Informed consent signed, * Patient with social protection Exclusion Criteria: * Patient with one or more documented contraindication to endodontic treatment, * Contraindication to the use of calcium silicate root canal sealer, such as an immature tooth or a known hypersensitivity to one component of the sealer formula, * Endodontic treatment on tooth with calcified root canal assessed radiographically, * Endodontic treatment on tooth with suspected perforation, * Patient with an uncontrolled systemic disease such as diabetes or thyroid disorders, or with an immunocompromised condition or who has undergone radiation therapy to the jaw. * Patient suffering from uncontrolled active periodontitis, not supported * Participation to another interventional clinical study at the same time, * Vulnerable subjects referred to in articles L.1121-5 to 8 and L.1122-1-2 of the Public Health Code and article 66 of Regulation (EU) 2017/745 on medical devices are excluded from the investigation (such as known pregnancy or lactation, patients with legal protection).