CompletedEarly Phase 1

S-ketamin Premedication in Pediatric EENT Surgery

China320 participantsStarted 2021-03-01

Plain-language summary

We aim to investigate the effects of premedication (intranasal or intravenous administration) of s-ketamin, dexmedetomidine, and combination for premedication in children undergoing ENT surgery.

Who can participate

Age range2 Years – 12 Years

SexALL

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Inclusion Criteria: * After obtaining the informed consent from their parents or proxies, the children aged 2 to 12 years, scheduled for elective ENT surgery, of American Society of Anesthesiologists (ASA) I or II were enrolled in this study. Exclusion Criteria: * Congenital heart diseases, congenital dysplasia, obstructive sleep apnea syndrome, upper respiratory tract infection, body mass index (BMI) ≥25, allergy to S-ketamin or dexmedetomidine, and severe liver or kidney disease.