Remote Ischemic Conditioning for Cerebral Amyloid Angiopathy-related Intracerebral Hemorrhage

Inclusion Criteria: * Age≥55 and ≤85. * The diagnosis of single or multiple spontaneous lobar cerebral hemorrhage is confirmed by brain CT scan(defined as possible or probable CAA by the Boston criteria) . * Hematoma volume of 10 to 50 ml. * Glasgow Coma Score (GCS)\>8. * Without surgery. * Starting RIC treatment between 24 and 48 hours of ictus. * Signed and dated informed consented is obtained. Exclusion Criteria: * Patients with suspected secondary ICH related to tumor, coagulopathy, ruptured aneurysm or arteriovenous malformation, or venous sinus thrombosis. * ICH concomitant with intraventricular hemorrhage, subdural hematoma, epidural hematoma subarachnoid hemorrhage or the condition of unstable vital signs which may be life-threatening. * Evidence of significant shift of midline brain structure (\>5mm) or herniation on brain imaging. * Contraindication to MRI scan, such as intracranial metal implants, cardiac pacemaker, severe claustrophobia, history of seizures and so on * Patients with a pre-existing neurological deficits (modified Ranks scale score \>2) or psychiatric disease that would confound the neurological or functional evaluations. * Use of warfarin or heparin within 7 days before the baseline visit * Contraindication for remote ischemic conditioning: severe soft tissue injury, limb deformities, fracture, atrial fibrillation or peripheral vascular disease in the upper limbs. * Life expectancy of less than 1 year due to co-morbid conditions. * Severe, susta…