Combination Facial Aesthetic Treatment in Millennials

Inclusion Criteria: * Date of birth between January 1, 1981 and December 31, 1996 * Naiveté to facial injections of botulinum toxin and dermal filler * Desire to receive all three facial cosmetic injectables in the study * Suitable candidate to receive facial injectables, as determined by clinician judgment * Provision of written informed consent for all study procedures * Stated willingness to comply with all study procedures and availability for the duration of the study Exclusion Criteria: * Desire to receive only one or two of the facial injectables * Dermatologic or medical conditions at the injection sites that may be exacerbated by the study procedures (e.g., severe acne, active infection, open sores or lesions, history of cold sores) * Pre-existing cardiovascular disease (e.g., heart failure, coronary artery disease) * Pre-existing swallowing or respiratory disorders (e.g., dysphagia, asthma, COPD) * Peripheral motor neuropathy disease, amyotrophic lateral sclerosis, or neuromuscular junctional disorders (e.g., myasthenia gravis, Lambert-Eaton syndrome) * Known hypersensitivity or allergies to any of the components of the administered drugs/devices in the study (e.g., Gram-positive bacterial proteins, lidocaine) * History of anaphylaxis or multiple severe allergies * History of a bleeding or coagulation disorder * Pregnant or breast-feeding * Current and/or scheduled use of the following medications: immunosuppressants, anticoagulants (e.g., warfarin, heparin, riva…