CompletedNot Applicable

Use of Prophylactic Steroids in the Prevention of Post-thyroidectomy Hypocalcaemia and Voice Dysfunction

192 participantsStarted 2014-01

Plain-language summary

Total thyroidectomy for benign surgical pathologies is associated with risks related to temporary hypocalcaemia and vocal quality dysfunction. Dexamethasone, as an anti-inflammatory steroid, has been proposed to have a physiological effect on hypocalcaemia and voice quality. Investigators conducted a double-blinded controlled trial to assess the effect of preoperative dexamethasone on the vocal dysfunction and hypocalcaemia following thyroidectomy

Who can participate

Age range18 Years – 60 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Benign thyroid condition. * Patients without any preoperative corrected hypocalcaemia and voice or vocal quality dysfunction. Exclusion Criteria: * Previous thyroid or neck surgery * Known vocal cord dysfunction on laryngoscopy * Hearing or voice problems * History of gastroesophageal reflux and stomach ulcer disease * Contraindications of steroids

What they're measuring

Hypocalcaemia

Timeframe: 3 days

Voice dysfunction

Timeframe: 24 hours

Trial details

NCT IDNCT04752852

SponsorHoly Family Hospital, Pakistan

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-12

View on ClinicalTrials.gov More Thyroid Diseases trials