TerminatedNot Applicable

Biological Function of Dreaming in Dreaming and Non-Dreaming Patients With PCA Infarction

Stopped: recruitment proved to be impossible for the necessary experimental non-dreaming group

Germany142 participantsStarted 2018-08-01

Plain-language summary

This study is a quasi-experimental between-group design. Using a prospective two-arm controlled exploratory study, data will be collected on an initial assessment of the effects of a specific neurological sample after thrombotic infarction (PCA infarction) who lost the ability to dream due to the infarction (experimental group) compared to a specific neurological sample after thrombotic infarction (PCA infarction) without loss of the ability to dream (comparison group) in terms of subjective and objective sleep quality and memory consolidation. Besides the importance to further elucidate the role of dreaming for sleep architecture and memory consolidation, the results of the evaluation are of great clinical relevance in a further scientific investigation regarding the treatment of a specifically neurological sample with acute thrombotic infarction.

Who can participate

Age range

18 Years – 90 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Exclusion criteria

. severe insomnia
. Restless Leg Syndrome (RLS)
. periodic movements of the extremities during sleep (PLMS), and
. obstructive sleep apnea syndrome (OSAS)

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change from pre- to post-sleep performance in memory of International Affective Picture System (IAPS)

Timeframe: pre-post sleep after a minimum of 8 hours sleep in sleep laboratory

Change from pre- to post-sleep performance in Finger-Tapping-Task (FTT)

Timeframe: pre-post sleep after a minimum of 8 hours sleep in sleep laboratory

Polysomnography (PSG)

Timeframe: 8 hours

Trial details

NCT IDNCT04749992

SponsorInternational Psychoanalytic University Berlin

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2024-03-08

View on ClinicalTrials.gov More Dream Disorder trials

Plain-language summary

Who can participate

Age range

18 Years – 90 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Exclusion criteria

. severe insomnia
. Restless Leg Syndrome (RLS)
. periodic movements of the extremities during sleep (PLMS), and
. obstructive sleep apnea syndrome (OSAS)

What they're measuring

Change from pre- to post-sleep performance in memory of International Affective Picture System (IAPS)

Timeframe: pre-post sleep after a minimum of 8 hours sleep in sleep laboratory

Change from pre- to post-sleep performance in Finger-Tapping-Task (FTT)

Timeframe: pre-post sleep after a minimum of 8 hours sleep in sleep laboratory

Polysomnography (PSG)

Timeframe: 8 hours