CompletedNot Applicable

Perioperative Troponin I and NT Pro-BNP in Lung Resection

Spain475 participantsStarted 2021-05-19

Plain-language summary

After lung resection, troponin elevation may be regulated by mechanisms other than myocardial ischemia. Perioperative natriuretic peptides measurement may help identify changes in ventricular function during thoracic surgery. Integrating both cardiac biomarkers may improve the predictive value for cardiovascular complications after lung resection.

Who can participate

Age range45 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age ≥45 years old * Patients undergoing elective surgery for lung resection Exclusion Criteria: * Patients undergoing urgent, emergent, or nonthoracic surgery * Patients or family did not consent to participate * Presence of symptoms related with infection or sepsis * Patients with a documented history of severe heart failure and/or ejection fraction lower than 30%

What they're measuring

NT-proBNP perioperative changes

Timeframe: Change from baseline NT-proBNP at two-days after surgery

TnI perioperative changes

Timeframe: Change from baseline TnI at two-days after surgery

Major cardiovascular complications

Timeframe: 30-days after surgery

Trial details

NCT IDNCT04749212

SponsorHospital Universitari Vall d'Hebron Research Institute

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2023-11-30

View on ClinicalTrials.gov More Cardiac Ischemia trials