CompletedPhase 4

Vaginal Progesterone 400mg v.s 200mg for Prevention of Preterm Labor in Twin Pregnancies

Egypt100 participantsStarted 2020-01-01

Plain-language summary

It is already known that the risk of preterm labor in twin pregnancy before 37 week is 8-9 fold higher compared to singletons, and progesterone supplementation can decrease the incidence of preterm labor in singleton pregnancy. There were studies that used 200mg vaginal progesterone with no effect on the result So this study aims To examine the effect of prophylactic vaginal progesterone 400mg v.s 200mg for prevention of preterm birth in twin pregnancies

Who can participate

Age range18 Years – 40 Years

SexFEMALE

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Inclusion criteria

✓. Primigravidae
✓. Twin pregnancies at gestational age 14 week.
✓. Cervical length more than 2 cm (because if 2cm or less they will undergo cervical cerclage.)

What they're measuring

Preterm labor

Timeframe: Before 37 weeks gestation

Trial details

NCT IDNCT04748562

SponsorAin Shams University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2020-08-01

View on ClinicalTrials.gov More Twin Pregnancy With Antenatal Problem trials