UnknownNot Applicable

Superior vs Temporal Laser Peripheral Iridotomy in Primary Angle Closure Suspects (PACS)

Canada200 participantsStarted 2020-11-25

Plain-language summary

Basic Study Design: Prospective, randomized, single-center, single-blinded study to compare dysphotopsias and pain recollection immediately 2 weeks, and 3 months after LPI in PACS patients who have a clear indication for bilateral LPI. Our null hypothesis is that there is no difference in dysphotopsia or pain levels by LPI position. Our alternate hypothesis is that there are more dysphotopsias superiorly and more pain temporally.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: \* clinical evidence of bilateral occludable angles (PACS) defined as: * Peripheral anterior synechia (PAS) absent and trabecular meshwork not visible in ≥6 clock hours under non-indentation gonioscopy, Along with, * absence of PAC or PACG, in both eyes. * macular and optic nerve OCT within the 95% range of the normative database for patients to be included in this study. Exclusion Criteria: * evidence of unilateral PACS, * a history suggestive of an acute angle closure attack (based on symptoms) documented intraocular pressure over 30 mmHg, * or any sign of Angle Closure Glaucoma (manifest glaucomatous neuropathy detected by OCT). * Patients with previous ocular surgeries will also be excluded.

What they're measuring

Dysphotopsias noted from baseline visit before procedure till 3 months after procedure

Timeframe: 3 months from baseline visit

Trial details

NCT IDNCT04741919

SponsorSunnybrook Health Sciences Centre

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-12-31

Contact for this trial

Catherine Birt, MD, FRCSC

416-480-5882 catherine.birt@sunnybrook.ca

View on ClinicalTrials.gov More Primary Angle Glaucoma Closure Suspect trials