Outcome of Dental Implant Therapy in Patients Treated With Antiresorptive Medication (NCT04741906) | Clinical Trial Compass
RecruitingNot Applicable
Outcome of Dental Implant Therapy in Patients Treated With Antiresorptive Medication
Denmark225 participantsStarted 2017-08-01
Plain-language summary
Aim of the study is to examine the feasibility of dental implant insertion in patients receiving high, adjuvant and low dose \> 4 years.
Who can participate
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patient with cancer or osteoporosis, treated with antiresorptive treatment.
* The patients should have sufficient compliance, this includes willingness to have the planned assessments
* The patient should have an expected life span at enrollment of at least 2 years.
* The local bone quality and quantity should be sufficient for implant insertion without bone augmentation and is classified according to the classification by Cawood \& Howell 1988.
Exclusion Criteria:
* \> 10 cigarettes daily
* HbA1c \> 53 mmol/mol
* Poor oral hygiene
* Poor general condition: ECOG score 3 or 4.
* Poor prognosis: Expected survival \<2 year is an exclusion cause.
* Presence of metastases of the liver brain.
* Poor local jaw bone quality acc. to Cawood classification stage 3 or 4.
* Unwillingness to comply with the planned assessments and recordings
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Dental implant survival
Timeframe: 3 months
2
Dental implant survival
Timeframe: 6 months
3
Dental implant survival
Timeframe: 18 months
4
Dental implant survival
Timeframe: 30 months
5
Dental Implant success
Timeframe: 30 months
6
Absence of medical related osteonecrosis of the jaw (MRONJ)