Pediatric SARS-CoV-2 Infections: Course of COVID-19, Immune Responses, Complications and Long-ter… (NCT04741412) | Clinical Trial Compass
CompletedNot Applicable
Pediatric SARS-CoV-2 Infections: Course of COVID-19, Immune Responses, Complications and Long-term Consequences
Germany231 participantsStarted 2020-06-03
Plain-language summary
Longitudinal study of 56 households with at least one member who had COVID-19 to compare the course of illness, immune responses, and long-term consequences of SARS-CoV-2 infection in HED patients with those of control subjects of the same age group. Complete households are investigated, including women who are pregnant when exposed to the virus and their newborn child(ren).
Who can participate
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* household with one or more members registered as patient(s) in the University Hospital Erlangen
* at least one person \<18 years of age
* at least one household member who has or had a SARS-CoV-2 infection confirmed by a positive PCR test, detection of specific antibodies against this virus, or by development of COVID-19 symptoms after being in close contact with a person known to be infected with SARS-CoV-2
* informed consent
Exclusion Criteria:
* missing informed consent of one or more household members
* language barriers to communication that would prevent informed consent
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
age-dependence of SARS-CoV-2 infection
Timeframe: 3 months from the point in time at which the first household member shows symptoms of COVID-19
2
percentage of household members infected by SARS-CoV-2
Timeframe: 3 months from the point in time at which the first household member shows symptoms of COVID-19
3
duration of primary COVID-19 symptoms
Timeframe: 2 months from the onset of COVID-19 symptoms
4
frequency of late-onset cardiovascular complications
Timeframe: 2-12 months from the onset of COVID-19 symptoms
5
frequency of postviral fatigue
Timeframe: 2-12 months from the onset of COVID-19 symptoms
6
frequency of noticeable temporary hair loss after COVID-19
Timeframe: 2-12 months from the onset of COVID-19 symptoms