A Study of Pembrolizumab (MK-3475) in Combination With Belzutifan (MK-6482) and Lenvatinib (MK-7902), or Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib, Versus Pembrolizumab and Lenvatinib, for Treatment of Advanced Clear Cell Renal Cell Carcinoma (MK-6482-012)

Inclusion Criteria: * Has histologically confirmed diagnosis of RCC with clear cell component. * Has received no prior systemic therapy for advanced ccRCC * Male participants are abstinent from heterosexual intercourse or agree to use contraception during and for at least 7 days after last dose of study intervention with belzutifan and lenvatinib. * Female participants are not pregnant or breastfeeding and are either not a woman of child-bearing potential (WOCBP) or use a contraceptive method that is highly effective or are abstinent from heterosexual intercourse during the intervention period and for at least 120 days after pembrolizumab or pembrolizumab/quavonlimab or for at least 30 days after last dose of lenvatinib or belzutifan, whichever occurs last * Has adequately controlled blood pressure with or without antihypertensive medications * Has adequate organ function. * Participants receiving bone resorptive therapy must have therapy initiated at least 2 weeks prior to randomization/allocation Exclusion Criteria: * Has a known additional malignancy that is progressing or has required active treatment within the past 3 years * Has had major surgery, other than nephrectomy within 4 weeks prior to randomization * Has known central nervous system (CNS) metastases and/or carcinomatous meningitis * Has received prior radiotherapy within 2 weeks prior to first dose of study intervention * Has hypoxia or requires intermittent supplemental oxygen or requires chronic supplement…