Efficacy of PRGF Supplementation After TMJ Arthrocentesis in Patients With TMJ Osteoarthritis

Inclusion Criteria: * Female * 40 - 80 years of age * Unilateral or bilateral TMJ arthralgia * Osteoarthritis diagnosis according to the Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD) * TMJ sounds (crepitus or click or both) * Mild-moderate masticatory muscle myalgia * History of non-surgical treatment for at least 6 weeks including such modalities as appliance therapy, NSAID therapy or physical modalities without resolution of pain Exclusion Criteria: * Contraindication to sedation including pregnancy or medical history * Rheumatologic disorders causing arthritis of the temporomandibular joint (i.e., rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis) * History of previous TMJ procedure including arthrocentesis, arthroscopy or arthrotomy * History of steroid injection in TMJ * TMJ pain greater than five years * History of narcotic drug use on a scheduled basis * Current active infection * Fibromyalgia