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The Incidence of Complete Posterior Vitreous Degeneration After Phacoemulsification

Thailand92 participantsStarted 2021-09-03

Plain-language summary

Intraocular surgery could induce vitreous degeneration and then abnormal posterior vitreous detachment (PVD) could occur including vitreoschisis and partial-thickness PVD. Vitreomacular interface (VMI) abnormalities such as epimacular membrane were observed following many intraocular surgeries. The incidence of peripheral break and epimacular membrane (EMM) after pneumatic retinopexy were 11.7% and 4-11%, respectively. Although multiple intravitreal anti-vascular endothelial growth factor (anti-VEGF) injections induced PVD of 5.6%, but peripheral break was reported as only 0.67%. The incidence of rhegmatogenous retinal detachment (RRD) after phacoemulsification is gradually increased with time. The accumulative risk of RRD was increased from 0.27% at 1 year to 1.27% at 20 years after phacoemulsification.

Who can participate

Age range50 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Cataract patients who was scheduled for phacoemulsification * Age \>50 years * No complete PVD was detected by OCT * Can be taken the wide-field OCT images * Written informed consent Exclusion Criteria: * Secondary cataract) * History of ocular trauma or head trauma * Systemic diseases that can cause the intraocular problems such as connective tissue disease * History of other ocular diseases such as glaucoma, uveitis and vitreoretinal disorders * History of intraocular laser treatment * History of intraocular surgery such as intravitreal drug injection Withdrawal Criteria: * Intraoperative complications such as posterior capsular rupture and zonule dialysis * Postoperative complications such as vitreous hemorrhage and postoperative endophthalmitis * Undergo the intraocular surgery during the follow-up period * Receiving the intraocular laser treatment during the follow-up period such as laser capsulotomy and panretinal photocoagulation * Having the ocular trauma or head trauma during the follow-up period

What they're measuring

The incidence of PVD after phacoemulsification

Timeframe: 12 months

Trial details

NCT IDNCT04727398

SponsorKhon Kaen University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-12-30

Contact for this trial

Suthasinee Sinawat, MD

+66 81 5454594 ssuthasinee@kku.ac.th