TerminatedNot Applicable

Development of Hardware and Software for Pulmonary Magnetic Resonance Imaging Using Inhaled Tracer Gases

Stopped: Funding constraints

Canada24 participantsStarted 2022-03-01

Plain-language summary

This is a single centre study. The overarching hypothesis of this study is that MRI with inhaled tracer gases can provide high quality images of lung function to complement conventional 1H MRI. The study interventions do not affect the standard of care.

Who can participate

Age range6 Years – 75 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Consent provided * Aged 6-75 years old * In good general health as evidenced by medical history * Meets MRI screening criteria Exclusion Criteria: * Has diagnosis of pulmonary disease * FEV1 \<70% * Requires supplemental oxygen * Has had a respiratory infection within the past 2 weeks * Pregnant or lactating\*

What they're measuring

The primary objective of this study is to develop the necessary imaging sequences, reconstruction algorithms, and hardware to acquire high quality lung images using HP 129Xe, 19F MRI, and conventional 1H MRI.

Timeframe: 5 years

Trial details

NCT IDNCT04726618

SponsorThe Hospital for Sick Children

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2024-04-09

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