This ClincialTrials.gov record originally corresponded to the protocol approved under IRB # 202370. The study was expanded to include stimulation and recordings approved under new IRB #211037. The participant data originally acquired from IRB# 202370 will be included in this new record: This study seeks to better understand the neural activity underlying neuro cognitive disorders. Resting state local field potential recordings will be collected from medically refractory epilepsy patients implanted with depth electrodes for seizure localization, and metrics of neural activity will be correlated with psychiatric symptoms as measured from questionnaires. Subjects will also participate in neuro cognitive tasks while neural recordings are performed, and/or receive neural stimulation through implanted depth electrodes. A better understanding of disordered neural activity underlying neuropsychiatric disorders may additionally contribute to novel methods for diagnosing, treating, and preventing these diseases.
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Neural activity correlating with the Center for Epidemiologic Studies Depression Scale - Revised (CESD-R)
Timeframe: During patient's epilepsy monitoring stay, approximately 15 minutes
Neural activity correlating with the State-Trait Anxiety Inventory (STAI)
Timeframe: During patient's epilepsy monitoring stay, approximately 15 minutes
Neural activity correlating with the Yale-Brown Obsessive Compulsive Scale (YBOCS)
Timeframe: During patient's epilepsy monitoring stay, approximately 15 minutes
Neural activity correlating with the Barratt Impulsiveness Scale (BIS11)
Timeframe: During patient's epilepsy monitoring stay, approximately 15 minutes
Local field potential changes in response to study tasks
Timeframe: During patient's epilepsy monitoring stay, approximately 20-30 minutes
Behavioral performance changes with stimulation
Timeframe: During patient's epilepsy monitoring stay, approximately 20-30 minutes
Single unit neuronal spiking changes in response to study tasks
Timeframe: During patient's epilepsy monitoring stay, approximately 20-30 minutes