The Effect of Ventilation Modes on Cerebral Oxymetry In Operation (NCT04723043) | Clinical Trial Compass
CompletedNot Applicable
The Effect of Ventilation Modes on Cerebral Oxymetry In Operation
Turkey (Türkiye)70 participantsStarted 2021-02-01
Plain-language summary
In laparoscopic cholecystectomy method, Insufflation of CO2 in abdominal cavity causes positioning of the diaphragm upwards, a decrease in lung's volume and its compliance, an increase in the airway resistance, mismatch between the atelectasis and the ventilation perfusion. Although there are numerous studies in laparoscopic surgery, only a few of them investigate the effects of laparoscopic surgery on the cardiopulmonary and the respiratory mechanics. The investigator aimed To examine the effects of pressure-controlled and volume-controlled ventilation modes on cerebral oximetry and blood gases in laparoscopic cholecystectomy operations.
Who can participate
Age range
18 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* ASA (American Society of Anesthesiology) score of 1 and 2
* body mass index \< 30 kg/m2
* planned elective laparoscopic cholecystectomy operation
* 18-65 years old
Exclusion Criteria:
* who are applied with emergency laparoscopic cholecystectomy operation
* ASA (American Society of Anesthesiology) score of 3 and above
* hematocrit value 30 and below
* body mass index\> 30 kg/m2
* major pulmonary disease (this condition was defined as having capacity and currency flow speed values that are below %70 in respiratory functional tests)
* patients with a history of thoracic surgery
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
NIRS
Timeframe: 0 to 3 hours (approximately)
2
oxygen saturation
Timeframe: 0 to 3 hours (approximately)
3
end-tidal carbon dioxide
Timeframe: 0 to 3 hours (approximately)
Trial details
NCT IDNCT04723043
SponsorSisli Hamidiye Etfal Training and Research Hospital