Nigella Sativa Oil Extract and Xenograft Bone Graft in Treatment of Infra-bony Defects

Inclusion Criteria: * systemically healthy patients were selected * patients who had not received any medications for the previous six months that may interfere with periodontal tissue health or healing. * Patients should demonstrate their ability to maintain good oral hygiene Exclusion Criteria: * • Smokers and pregnant patients. * Medically compromised patients and systemic conditions precluding periodontal surgery. * Subjects who do not comply with oral hygiene measures as evidenced in recall visits. * Restoration or caries in the site to be treated or non-vital tooth * Restoration or caries in the site to be treated or non-vital tooth