This is a retrospective/prospective observational multicentric trial on patients with bone metastases from NENs. General objectives: * To trace on a national scale the frequency of bone metastases in patients with neuroendocrine neoplasm (NEN) and their clinical management. * To correlate clinical and biological factors to clinical outcomes. * To centralise and to make homogeneous clinical, pathological, instrumental and therapeutic information. * To set up a database and to acquire biological material for studying predictive and prognostic biomarkers.
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Overall survival
Timeframe: 01/2021 - 12/2021
Influence of skeletal related events (SRE) on survival
Timeframe: 01/2021 - 12/2021
Correlation between SRE and time from bone metastasis and SRE, site of one metastases, number of bone metastases, morphology of bone metastases, LDH
Timeframe: 01/2021 - 12/2021
Influence of the use of bisphosphonates or RANK-ligands
Timeframe: 01/2021 - 12/2021