Ultrasound-guided TAP Block Vs Local Wound Infiltration for Analgesia After Cesarean Section. (NCT04711096) | Clinical Trial Compass
CompletedNot Applicable
Ultrasound-guided TAP Block Vs Local Wound Infiltration for Analgesia After Cesarean Section.
Egypt300 participantsStarted 2021-01-01
Plain-language summary
Adequate pain control after cesarean delivery is a major concern for both parturients and obstetrician, and it usually comprise a combination of systemic and regional techniques. The transversus abdominis plane (TAP) block, affecting the nerves supplying the anterior abdominal wall, is a recently introduced, promising regional analgesic technique for a variety of abdominal and pelvic surgeries including cesarean delivery .
Infiltration of local anesthetic into the surgical wound (either as a single shot or using indwelling catheters) has long been used for postoperative analgesia, Both the TAP block and wound infiltration, are superior to placebo, however, it is unknown which of them provides better analgesia after cesarean delivery because of a scarcity of randomized clinical trials.
This study aimed to compare bilateral US guidedTAP block with single-shot local anesthetic wound infiltration for analgesia after cesarean delivery performed under general anesthesia. The investigators hypothesized that the TAP block would decrease postoperative cumulative opioid consumption at 24 hours.
Who can participate
Age range
18 Years – 40 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* • Patients undergoing elective cesarean section under general anathesia
* Pfannenstiel Skin Incision
* Age between 18 and 40 years old
* BMI between 18 and 35 kg/m2
Exclusion Criteria:
* • Patient refusal.
* BMI\<18 kg/m2 or\>35 (require different dose of analgesia)
* Height \<150 or \> 180 cm (require different dose of analgesia)
* Patients with any neurological deficit due to neuropathy and pain score affection
* Patients with bleeding disorders which may lead to hematoma
* HTN (Vasculopathy which can lead to hematoma).
* Cardiac disease ( Vasculopathy on anticoagulant which can lead to hematoma)
* DM (decrease systemic and local immunity which can lead to abscess at injection site and due to neuropathy and pain score affection).
* Liver disease (defective clotting factors).
* A history of relevant drug allergy or Hypersensitivity to any of the drugs used in the study due to impair of proper follow up of pain postoperative
* History of recent opioid exposure due to affection on pain score
* Local skin infection due to abscess formation
* Obstetric complications e.g placenta previa and rupture uterus due to extensive tissue damage and dissection
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Postoperative pain severity assessed by the Numerical Rating Scale (NRS) pain score at 1,2,4,6, 12, and 24 hours
Timeframe: 24 hours after the procedure
2
The duration of analgesia achieved by each type of block assessed by the time of first postoperative pethidine dose required.