CompletedNot Applicable

AVS After 1mg DST to Determine Subtype in PA

China110 participantsStarted 2021-01-08

Plain-language summary

To compare the effect of different procedures of AVS(after 1mg DST or not) in determining the subtypes and long-term outcomes of PA

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

✕. Pregnant or lactating women
✕. Patients with a history of malignant tumors or complicated with severe heart disease, eGFR\<30ml/min/1.73m2, severe anemia (Hb\<60g/L), stroke or acute coronary syndrome within 3 months, severe liver disease
✕. Having contraindications or refusal to undergo AVS or unilateral adrenalectomy, or allergy to ACTH;
✕. PA combined with Cushing syndrome (including subclinical Cushing); or considering glucocorticoid-suppressible aldosteronism (GRA) or adrenocortical carcinoma;

Complete biochemical remission

Timeframe: 1year

Complete clinical remission

Timeframe: 1 year

NCT IDNCT04709185

SponsorShanghai Zhongshan Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-10-30