CompletedNot Applicable

Therapy of Pragmatic Disorders in Brain-damaged Individuals

Switzerland2 participantsStarted 2020-06-03

Plain-language summary

This study aims to assess speech therapy's effectiveness in understanding other people's thoughts (implied) using written stories. The main objective is to examine whether the therapy improves understanding of the stories worked on in the sessions. We also explore whether the observed progress is maintained one month after the end of treatment and whether it is generalized to neuropsychological tests, video material, and the participants' daily lives. This therapy will be administered to four individuals with brain lesions, for six weeks, at the rate of two weekly sessions of one hour.

Who can participate

Age range20 Years – 65 Years

SexALL

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Inclusion Criteria: * Have been the victim, in adulthood, of a moderate to severe traumatic brain injury (TBI) or a stroke, with at least right frontal lesions (objectified by imaging). The time between the TBI or stroke and participation in this study should be greater than six months. * Be of French mother tongue or have an excellent mastery of French. * Be between 20 and 65 years old. * Be right-handed * Present problems in the understanding of non-literal language (irony, indirect requests), objectified by a neuropsychological examination. Exclusion Criteria: * Have a history of psychiatric disorder affecting social cognition (according to DSM-V criteria), and more specifically: autism, schizophrenia, bipolar disorders, major depressive disorders, borderline personality disorders, generalized anxiety disorders, obsessive-compulsive disorders, phobia social and eating disorders (anorexia, bulimia). * Have chronic symptoms of an alcohol or drug dependence disorder (according to DSM-V criteria). * Have significant uncorrected vision and/or hearing problems. * Have aphasia and/or significant reading and comprehension problems. * Present significant spatial neglect. * Present an impaired capacity for judgment and discernment, objectified by a neuropsychological evaluation. * Have been the victim of several TBI or stroke

What they're measuring

Change from the score on the written task of comprehension of non-literal language 48 hours after the end of the therapy

Timeframe: Baselines, 24-48 hours after the last session of the therapy

Change from the score on the written task of comprehension of non-literal language 1 month after the end of the therapy

Timeframe: Baselines, 1 month-follow-up

Maintenance from the score on the written task of comprehension of non-literal language 1 month after the end of the therapy

Timeframe: 24-48 hours after the last session of the therapy, 1 month-follow-up

Trial details

NCT IDNCT04708561

SponsorUniversity of Neuchatel

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-10-31

View on ClinicalTrials.gov More Brain Injuries, Traumatic trials