UnknownNot Applicable

Lens Extraction Combined With Goniosynechialysis Versus Trabeculectomy

China316 participantsStarted 2021-01-30

Plain-language summary

To compare the effectiveness of lens extraction combined with goniosynechialysis and trabeculectomy in treating advanced angle-closure glaucoma.

Age range40 Years – 80 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

✓. Age between 40 years old to 80 years old
✓. more than 180-degree synechial closure of anterior chamber angle on gonioscopy
✓. IOP higher than 21mmHg under the use of more than two anti-glaucoma eye drops
✓. mean deviation of visual field worse than -12dB on Humphrey 24-2
✓. phakic eyes

✕. Snellen visual acuity worse than 0.02
✕. history of ocular trauma
✕. uveitis
✕. previous ocular surgeries
✕. significant conjunctival scar
✕. visible neovascular on iris or anterior chamber angle
✕. other severe eye diseases that would affect visual function significantly, such as age-related macular degeneration and pathogenic myopia.

Intraocular pressure (IOP) change at one month

Timeframe: one month

IOP change at three months

Timeframe: three months

IOP change at six months

Timeframe: six months

IOP change at one year

Timeframe: one year

IOP change at two years

Timeframe: two years

IOP change at three years

Timeframe: three years

Best corrected visual acuity at one month

Timeframe: one month

Best corrected visual acuity at three months

Timeframe: three months

Best corrected visual acuity at six months

NCT IDNCT04703712

SponsorEye & ENT Hospital of Fudan University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-12

Feng Gao, Doctor