UnknownNot Applicable

Longitudinal Follow-up Study About Complex Regional Pain Syndrome (CRPS) Patients

Switzerland110 participantsStarted 2019-03-14

Plain-language summary

Complex regional pain syndrome (CRPS) is a post-traumatic chronic pain condition characterized by pain and other symptoms typically affecting a distal limb. Relatively little is known about the prognosis of the course of CRPS .Currently there is no specific test to diagnose CRPS. The primary objective of the study is to investigate prospectively the evolution of CRPS and the impact of the psychosocial factors on health status, recovery, quality of life, and working status of CRPS patients. The secondary objective of the study is to measure blood parameters in CRPS patients to investigate their evolution during the course of CRPS, and maybe to identify distinctive biomarkers associate with CRPS and that could be potential candidate for diagnosis.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria for patients: * CRPS Type I (fulfilling Budapest criteria for research) * Suffering of CRPS in a distal limb (hand or foot) * Age \>18 years * Pain lasting less than 6 months * Good understanding of the French language Inclusion criteria for control: * Not suffering from chronic pain, including CRPS * Age \>18 years Exclusion Criteria for both group: * Known or suspected non-compliance, drug or alcohol abuse, * Inability to follow the procedures of the study, e.g. due to language problems, severe psychological disorders, dementia, etc * For blood sample: diabetes and history of hepatitis B, C, D or HIV infection

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

patient return to work (RTW)

Timeframe: 3 months after inclusion

patient return to work (RTW)

Timeframe: 6 months after inclusion

patient return to work (RTW)

Timeframe: 1 year after inclusion

patient return to work (RTW)

Timeframe: 2 years after inclusion

Recovery of CRPS

Timeframe: 3 months after inclusion

Recovery of CRPS

Timeframe: 6 months after inclusion

Recovery of CRPS

Timeframe: 1 year after inclusion

Recovery of CRPS

Timeframe: 2 years after inclusion

Trial details

NCT IDNCT04703647

SponsorClinique Romande de Readaptation

Sponsor typeNETWORK

Study typeOBSERVATIONAL

Primary completion2024-12-01

Contact for this trial

michel Konzelmann, MD

+41 79 314 84 84 michel.konzelmann@crr-suva.ch

View on ClinicalTrials.gov More Complex Regional Pain Syndrome Type I trials

Plain-language summary

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

patient return to work (RTW)

Timeframe: 3 months after inclusion

patient return to work (RTW)

Timeframe: 6 months after inclusion

patient return to work (RTW)

Timeframe: 1 year after inclusion

patient return to work (RTW)

Timeframe: 2 years after inclusion

Recovery of CRPS

Timeframe: 3 months after inclusion

Recovery of CRPS

Timeframe: 6 months after inclusion

Recovery of CRPS

Timeframe: 1 year after inclusion

Recovery of CRPS

Timeframe: 2 years after inclusion