Serratus Anterior Plane Block Versus Standard of Care After Totally Endoscopic Aortic Valve Replacement

Inclusion Criteria: * Scheduled for elective aortic valve replacement surgery via right anterolateral thoracotomy * Adult patients (minimally 18 years old) * EuroScore ii \< 3% * Bodyweight \> 50 kg Exclusion Criteria: * Refusal to participate * Inability to communicate due to language or neurologic barriers * Inability to control and self-administer opioids with PCIA or to comprehend the NRS pain score due to confusion or learning difficulties * Chronic use of opioids * Chronic use of analgesic antidepressants and/or antiepileptics * History of major trauma or surgery to right chest wall * History of chronic pain at right chest wall * Allergy to opioids and/or local anesthetics * Allergy to acetaminophen * Morbid obesity (BMI \> 35) * Pregnancy * Peroperative events compromising early postoperative recovery (aortic dissection, systolic anterior motion of the mitral valve, cardiac tamponade, ..)