CompletedNot Applicable

Comparison of Efficacy of Less Invasive Surfactant Treatment Under Nasal CPAP and Nasal IPPV

Turkey (Türkiye)85 participantsStarted 2020-10-01

Plain-language summary

Non invasive ventilation is important in the care of preterm infants with respiratory failure, and surfactant treatment can be use with non invasive ventilation. However, there is no consensus on the best non-invasive ventilation mode for surfactant treatment in preterm infants. Objective: To compare the effectiveness of nasal intermittent positive pressure ventilation (NIPPV) versus nasal continuous positive airway pressure (CPAP) in preterm infants ≤ 29 week gestational age.

Who can participate

Age range24 Weeks – 29 Weeks

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Gestational age 24 -29 week * Clinical and radiological diagnosis of RDS * Born in a hospital with a study center * Spontaneous breathing * Within the first 6 hours * Non-invasive ventilation and FiO2 requirement \>0.30 * Parental concent Exclusion Criteria: * Major congenital malformations * Need of mechanical ventiation * Need of entubation in delivery room * Air weak syndrome * No parental concent

What they're measuring

Treatment failure within 72 hours after randomization 72 hours after randomization

Timeframe: within 72 hours after randomization

Trial details

NCT IDNCT04698473

SponsorUludag University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-05-01

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