CompletedNot Applicable

Topical Tranexamic Acid Versus Topical Vitamin C With Microneedling in Periorbital Hyperpigmentation; Comparative Study

Egypt60 participantsStarted 2019-11-01

Plain-language summary

Both vitamin C 20% and tranexamic acid 5mg/ml combined with microneedling were used for treatment of periorbital hyperpigmentation in a comparative pattern and both resulted in significant improvement of periorbital hyperpigmentation by dermoscopic and clinical evaluation with no statistically significant difference between them in addition to improvement of patients' visual analogue score (VAS) and dermatology life quality index (DLQI).

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * both genders. * age ≥ 18 years. * pigmentary, vascular and mixed types of dark halos Exclusion Criteria: * pregnancy and lactation * patients who received treatment in the past 3 months * patients with active dermatologic diseases or history of atopic dermatitis. * history of allergy to tranexamic acid or vitamin c * history of keloid or hypertrophic scars * pure structural type of dark halos, pigmentary demarcation lines

What they're measuring

evaluation of effectiveness of tranexamic acid in periorbital hyperpigmentation

Timeframe: 10 weeks (patients are assissed 1 month after the last session)