OTC Naproxen and Acetaminophen Anti-Inflammatory Action in Dental Implant Patients

Inclusion Criteria: * Subject requires surgical placement of one or two (adjacent) dental implants * Ability to read and sign informed consent * Males and females for 18-75 years of age * Non-smokers * Negative urine drug screen Exclusion Criteria * Advanced periodontal disease (\>20% Clinical Attachment Loss \>20% radiographic bone loss) * History of bisphosphonate usage * Medical history or medical condition that makes any of the study medications (naproxen sodium, acetaminophen, tramadol, etc.) inappropriate treatment options including any scheduled or recent cardiac procedures (within 6 months), a history of GI ulcers, liver or kidney disease, and anticoagulant or lithium intake. * History of an allergic reaction to any pain reliever/fever reducer * Contraindication to opioid use * Positive urine drug screen for drugs of abuse unless on stable doses of a non-analgesic drug for a legitimate medical purpose * Pregnancy - A urine pregnancy test will be performed immediately before the scheduled surgery on all women of child-bearing potential * Local or systemic diseases that affects wound healing and inflammatory biomarkers (diabetes, autoimmune (rheumatoid arthritis), or inflammatory disorders - osteoarthritis is allowed). * Smokers on this pilot study because it can affect levels of inflammatory biomarkers - a urine cotinine test will be performed immediately prior to the scheduled surgery on all subjects even if participant denies smoking history * History of systemic …