UnknownPhase 2

Use of Topical Solasodine of Solanum Melongena Peel Origin in the Treatment of Palmar Arsenic Keratosis

Bangladesh20 participantsStarted 2018-09-23

Plain-language summary

Arsenic is one of the largest mass poisonings in Bangladesh. Arsenic keratosis of the palm and sole is a common feature of arsenicosis. Brinjal or eggplant ubiquitous vegetable found in different parts of the world, including Bangladesh, scientifically known as Solanum melongena. A study showed ointment containing crude extract of Solanum melongena peel origin is effective in arsenic keratosis. Solasodine is one of the active compounds of Solanum melongena peel. In the current study, an ointment containing a single compound solasodine isolated from Solanum melongena peel . The ointment made from solasodine extract was distributed among arsenic keratosis patients to see the effect.

Who can participate

Age range18 Years – 60 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Presence of moderate to severe palmar arsenical keratosis * Drinking arsenic-contaminated water for at least six months * Patient voluntarily agreed to participate Exclusion Criteria: * Age less than 18 years or more than 60 years * Pregnant and nursing mother * Skin diseases like atopic dermatitis eczema and psoriasis * Patient allergic to brinjal (eggplant) * Patient taken any treatment of arsenicosis for the last six months

What they're measuring

Arsenical Keratotic nodular size of the palm

Timeframe: 12 weeks

Trial details

NCT IDNCT04693000

SponsorBangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-01-15

View on ClinicalTrials.gov More Keratotic Nodular Size trials