UnknownNot Applicable

May the Risk of PHLF be Predicted With Preoperative Liver Gadoxetate MRI

Denmark, Finland, Norway200 participantsStarted 2020-12-29

Plain-language summary

Post hepatectomy liver failure (PHLF) is one of the most severe complications after liver re-section. Preoperative evaluation of liver function is complicated and imprecise. The volume and function needed for each individual patient is unknown and the methods used for evaluation are uncertain. Preoperative MRI with Gadolinium may give dynamic information regarding liver function correlating with postoperative liver failure. A retrospective analysis will be performed regarding this topic.

Who can participate

Age range18 Years

SexALL

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Inclusion criteria

✓. Patients who have had a Primovist MRI within 8 weeks before hemihepatectomy or extended hemi-hepatectomy +/- bile duct anastomosis independent of diagnosis.
✓. Patients with cirrhosis who have had a Primovist MRI within 8 weeks before resection of more than one liver segment
✓. Patients who had liver volume augmentation with a pre-operative Primovist MRI less than 2 weeks before resection
✓. Patients who have had a Primovist MRI within 6 weeks be-fore any liver resection where PHLF or death within 90 days occurred.

Exclusion criteria

✕. \<18 years of age
✕. Resection was not performed -

What they're measuring

Contrast dynamics of Gadoxetate MRI correlation with the risk of PHLF.

Timeframe: 2 years

Trial details

NCT IDNCT04692259

SponsorUniversity Hospital, Linkoeping

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-02-28

Contact for this trial

Per Sandström, Prof

+46734058581 per.sandstrom@liu.se

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