Active — Not RecruitingNot Applicable

The Longitudinal Relationship of HU Adherence to HRQOL, Barriers to Adherence and Habit in SCD.

United States68 participantsStarted 2021-03-02

Plain-language summary

The primary objective of this study is to better understand factors contributing to variations in hydroxyurea (HU) adherence behavior in adolescents and young adults (AYA) with sickle cell disease (SCD). To meet this objective, the researchers will conduct a prospective cohort study to determine the longitudinal relationship between HU adherence and health-related quality of life (HRQOL) overtime among AYA with SCD. The long-term goal of this research is to promote medication adherence behavior and improve health outcomes in AYA with SCD.

Who can participate

Age range12 Years – 21 Years

SexALL

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Inclusion Criteria: * Age 12-21 years old * Any sickle cell disease genotype * On steady state of hydroxyurea for 2 months * Own or have access to a smartphone * Parents of patients that meet the eligibility criteria and are enrolled in the study will be included Exclusion Criteria: * Patients with recent hospitalizations within the past 7 days

What they're measuring

Hydroxyurea adherence rate

Timeframe: 12 months

Trial details

NCT IDNCT04691323

SponsorAnn & Robert H Lurie Children's Hospital of Chicago

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-06-01

View on ClinicalTrials.gov More Sickle Cell Disease trials