CompletedNot Applicable

Hyperglycemia in Patients With Takotsubo Syndrome

Italy40 participantsStarted 2013-01-01

Plain-language summary

Patients with Takotsubo cardiomiopathy (TTC) have over-inflammation and over-sympathetic tone. However, these conditions could cause higher rate of heart failure (HF) events and deaths at 2 years of follow-up. Conversely, hyperglycemia vs. normoglycemia could result in over expression of inflammatory markers and catecholamines thta could result in higher rate of HF and deaths at 2 years of follow-up in TTC patients.

Who can participate

Age range18 Years – 75 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * acute onset of a cardiovascular event, usually associated with substernal chest pain, initially regarded as STEMI/evolving coronary syndrome; * cardiac biomarker modifications (creatine kinase-MB and troponin I); * systolic dysfunction, predominantly characterized by akinesia/hypokinesia of the mid-to-distal portion of the left ventricle (LV) chamber, with hyper-contractile basal LV. Exclusion Criteria: * patients with previous previous myocardial infarction; * patients with previous TTC event; * patients affected by chronic kidney, liver, and cerebrovascular diseases.

What they're measuring

The number of HF events

Timeframe: 12 months

Trial details

NCT IDNCT04684004

SponsorUniversity of Campania Luigi Vanvitelli

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2017-01-01

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