CompletedPhase 4

Flagyl Microbiome in Crohn's Disease

United States4 participantsStarted 2021-03-21

Plain-language summary

This study will compare the types of bacteria in the colon before and after colon resection surgery. The investigator will also compare standard post-operative antibiotic treatment to flagyl (metronidazole) treatment post-operatively to see if giving the antibiotic, decreases the incidence of return of Crohn's disease.

Who can participate

Age range20 Years – 80 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 20-80 years old who is deemed an acceptable surgical candidate for ileocolic resection. Exclusion Criteria: * any patients that are dependent on total parenteral nutrition and unable to tolerate oral intake * patients who will undergo resection but will have an ileostomy created * patients on maintenance antibiotics for their disease

What they're measuring

Change in bacteria in the gut

Timeframe: six months

Trial details

NCT IDNCT04682522

SponsorUniversity of Louisville

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-08-15

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