The Effect of Tamsulosin on Postoperative Urinary Retention

Inclusion Criteria: * Stage II or greater pelvic organ prolapse in \> 1 vaginal compartment * Plan for multicompartment native tissue vaginal repair (which would include any combination of uterosacral ligament suspension, sacrospinous ligament suspension, cystocele and/or rectocele repair, with or without hysterectomy and with or without concomitant mid-urethral sling) or vaginal closure with female pelvic medicine and reconstructive surgery (FPMRS) - trained surgeons at Wake Forest Baptist Health * Participation in Enhanced-Recovery-After-Surgery protocol with plan for same-day hospital discharge * Willing to remain compliant with Investigation Product (IP) Exclusion Criteria: * Intraoperative complication necessitating prolonged bladder drainage or placement of a vaginal pack x 24 hours (patients would exit study after randomization and will be excluded from the per-protocol analysis) * Patients whose surgical plan would necessitate a voiding trial on postop day \>0 * Less than 21 years of age * Unable to understand English * Patients who are scheduled to undergo combined colorectal procedures such as rectopexy, sphincteroplasty * Patient with known allergy to Tamsulosin or sulfa drugs * Patients with upcoming cataract surgery * Patient with orthostatic hypotension * History of postvoid residual (PVR\>150) prior to surgery with prolapse reduction * Patients with hypertension on alpha-blockers * Single compartment prolapse repair (anterior or posterior repair only) * Use …