MINS, AKI and Pulmonary Pathology in Patients Undergoing Acute Abdominal Surgery (NCT04681508) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
MINS, AKI and Pulmonary Pathology in Patients Undergoing Acute Abdominal Surgery
Denmark600 participantsStarted 2021-03-01
Plain-language summary
Explorative study to investigate potential predictors of myocardial injury, acute kidney injury and pulmonary disorder after acute high-risk abdominal surgery.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Adults (≥18 years).
* Patients included in the AHA regimen undergoing CT on suspicion acute high-risk abdominal disorder e.g.g bowel obstruction GI perforation or ischemia, and need of emergency abdominal surgery, either laparoscopic surgery or laparotomy.
* Able to speak Danish. In case Danish was not spoken an interpreter was used to obtain the informed consent.
* Able to give informed consent.
Exclusion Criteria:
* Patients who cannot give informed consent to participate in the study 15 minutes after receiving verbal information regarding the study.
* Known chronic kidney disease requiring dialysis at the time of admission (only exclusion criteria for the part of the study relating to AKI).
* Patients included in the AHA regimen, but conservative treatment is chosen (only exclusion criteria for the part of the study relating to MINS and AKI).
* Patients not resident in Denmark.
* Patients not able to give informed consent.
* Patient not able to speak Danish and not enough time to obtain an interpreter.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Since this study is actively tracking serious complications like heart injury, kidney injury, and lung problems after emergency abdominal surgery, can you tell me whether my own surgical team is already monitoring for these same things as part of my care, regardless of this trial?
2This trial is listed as 'active not recruiting,' which means I likely can't enroll — but given that it's measuring mortality rates and organ complications after acute abdominal surgery, are there any findings or protocols from studies like this one that might already be influencing how my surgery and recovery would be managed?
3The study is measuring what proportion of patients develop myocardial injury — meaning heart stress — after non-cardiac surgery like this. How would my doctors be watching for that after my procedure, and what would they do if they detected it?
4Since acute kidney injury is one of the specific outcomes being tracked in this trial, are there steps my care team would take before or after surgery to protect my kidneys, especially given that emergency abdominal surgery carries higher risks than planned procedures?
5This trial is observational in nature and focuses on understanding how often these complications occur rather than testing a new treatment — so is there a different trial or a standard-of-care protocol that might more directly address preventing these complications in my specific situation?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Proportion of patients with myocardial injury af non-cardiac surgery
Timeframe: 30 days
2
Mortality rate
Timeframe: 30 days
3
Mortality rate
Timeframe: 90 days
4
Mortality rate
Timeframe: 1 year
5
Acute kidney Injury
Timeframe: 30 days
6
Proportion of patients with pulmonary pathology
Timeframe: 1 day
7
Proportion of patients with pulmonary complications