CompletedNot Applicable

Evaluation of Blood Biomarkers as an Indicator of Delayed Neurocognitive Recovery

South Korea82 participantsStarted 2021-01-06

Plain-language summary

Delayed neurocognitive recovery is defined as a cognitive decline arising after surgery. In the present study, the authors evaluate the level of D-Amino Acid Oxidase, D-serine and Serine racemase in blood as an indicator of delayed neurocognitive recovery after cardiac surgery.

Who can participate

Age range55 Years

SexALL

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Inclusion Criteria: * Patients scheduled for elective cardiac surgery Exclusion Criteria: * MMSE \<24 * History of psychological or neurological diseases * Illiteracy * Preoperative delirium * Vision and hearing impairment

What they're measuring

Change of concentration of D-Amino Acid Oxidase in blood at 1, 2, and 7 day after surgery

Timeframe: Before surgery and at 1, 2, and 7 day after surgery

Trial details

NCT IDNCT04679259

SponsorSMG-SNU Boramae Medical Center

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-10-22

View on ClinicalTrials.gov More Postoperative Cognitive Dysfunction trials