RecruitingNot Applicable

A Personalized Surveillance and Intervention Protocol for Duodenal and Gastric Polyposis in Patients With Familial Adenomatous Polyposis

United States, Netherlands1,000 participantsStarted 2020-11-24

Plain-language summary

The purpose of this study is to determine the efficacy and safety of a personalized surveillance and intervention protocol for duodenal and gastric polyposis in patients with familial adenomatous polyposis (FAP)

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Diagnosis of FAP, at least one of following: genetic diagnosis (proven APC germline mutation) and/or clinical diagnosis (\>100 colorectal adenomas in combination with a positive family history of FAP) * Age 18 years or older Exclusion Criteria: * Endoscopic removal of all polyps with an indication for removal not possible/feasible * Gastric or duodenal cancer at baseline endoscopy * Need for surgery

What they're measuring

Advanced neoplasia

Timeframe: Up to 5 years

Trial details

NCT IDNCT04677998

SponsorAcademisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-11

View on ClinicalTrials.gov More Familial Adenomatous Polyposis trials