Lung Ultrasound to Assess Aeration Loss After Lung Resection Surgery (NCT04677309) | Clinical Trial Compass
CompletedNot Applicable
Lung Ultrasound to Assess Aeration Loss After Lung Resection Surgery
Spain32 participantsStarted 2020-12-20
Plain-language summary
The purpose of this prospective observational study is to assess perioperative changes in lung aeration after lung resection surgery using lung ultrasound, and to explore their relationship with oxygenation, inflammatory biomarkers, cardiac stress markers and diaphragmatic function.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age \> 18
* ASA I-III
* Non-small cell lung neoplasm
* Elective lobectomy
* Under one-lung ventilation
Exclusion Criteria:
* pregnancy
* Diagnosed pulmonary fibrosis
* Scheduled surgery limited to biopsy
* Surgery that includes resection of the thoracic wall or the diaphragm
* Predicted FEV1 \< 40%
* Neoplasm metastasis
* Obesity class II or more (BMI ≥ 35 kg/m\^2)
* Risk of malnutrition CONUT score \> 1
* Hemoglobin \< 10 g/dl
* Chronic kidney failure: glomerular filtration \< 60 ml/min/m\^2, nephrectomy, kidney transplantation
* Treatment with corticosteroids or immunosuppressive agents 3 months before surgery
* Transfusion of blood products during the previous 10 days
* Heart failure (New York Heart Association Functional Class 3 or 4) during the week before surgery.
* Heart valve diseases over stage B of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines 2014
* Previously documented elevated left atrial pressure or cardiac disease associated with elevated left-sided filling pressures.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in lung aeration after lung resection surgery assessed by lung ultrasound score
Timeframe: preoperative vs immediate postoperative period vs 24 hours after surgery