UnknownNot Applicable

Biomarkers in the Diagnosis of Acute Compartment Syndrome

Sweden250 participantsStarted 2018-04-05

Plain-language summary

This prospective multinational, multicentre cohort study aims to investigate the hypothesis that biomarkers of muscle cell damage can predict acute compartment syndrome in patients with tibial fractures.

Who can participate

Age range15 Years – 65 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Tibial fracture group Inclusion Criteria: \- Traumatic tibial fracture Exclusion Criteria: * Malignancy * Acute myocardial infarction * Kidney failure (GFR ≤35 ml/min) * Muscle disease * Paraplegia/tetraplegia Non-fracture group Inclusion Criteria: \- Suspected acute compartment syndrome Exclusion Criteria: * Malignancy * Acute myocardial infarction * Kidney failure (GFR ≤35 ml/min) * Muscle disease * Paraplegia/tetraplegia * Associated fracture * Acute vascular event

What they're measuring

Peak levels of P-myoglobin and P-creatine phosphokinase

Timeframe: Up to 5 days

Trial details

NCT IDNCT04674592

SponsorUniversity Hospital, Linkoeping

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2023-06

Contact for this trial

Jörg Schilcher, MD, PhD

+46101030000 jorg.schilcher@liu.se

View on ClinicalTrials.gov More Acute Compartment Syndrome trials