Biomarkers in Nasal Samples of Seasonal Allergic Rhinitics

Inclusion Criteria: (Allergic Rhinitics): * Non-smoking males and females aged 18-70 years, inclusive * History of Seasonal Allergic Rhinitis defined by: Sensitization to at least one seasonal aeroallergen via skin prick testing (wheal =3 mm than negative control), AND History of physician-diagnosed seasonal allergic rhinitis, OR Symptoms consistent with seasonal allergic rhinitis, such as runny nose, nasal congestion, sneezing, or nasal pruritis. * Have lived in the South Atlantic region (Virginia, North and South Carolina, Georgia, Alabama, Florida) for at least 1 year prior to study entry. * Willing to undergo written informed consent indicating that the participant has been informed of all pertinent aspects of the study before any assessment is performed. * Willing and able to comply with scheduled visits, nasal sample collection, and other study procedures. (Non-allergic): * Non-smoking males and females aged 18-70 years, inclusive * No history of physician-diagnosed allergic rhinitis and no history of seasonal runny nose,nasal congestion, sneezing or nasal pruritis. * Negative results to a panel of aeroallergens via skin prick testing * Willingness to undergo written informed consent indicating that the participant has been informed of all pertinent aspects of the study before any assessment is performed. * Willing and able to comply with scheduled visits, nasal sample collection, and other study procedures. Exclusion Criteria: * Symptomatic perennial AR (for ex…