CompletedNot Applicable

Management of Post Dural Pucture Headache After Lower Limb Surgeries: Oral Prednisolone vs Oral Pregabalin

Egypt63 participantsStarted 2020-12-10

Plain-language summary

The aim of this study is to compare between oral prednisolone and oral pregabalin in management of PDPH to detect effectiveness of the treatment in reducing severity of PDPH, total rescue analgesic consumption and adverse effects of prednisolone and pregabalin in patients undergoing lower limb surgery.

Who can participate

Age range18 Years – 65 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * \- Both gender. * Age: 18- 65 years old. * Body Mass Index 20-30 kg/m2 * American Society of Anesthesiologist (ASA) physical status I - II. * Patients are diagnosed as PDPH according to criteria of International Headache Society (IHS) after lower limb surgeries . Exclusion Criteria: * \- Allergy to study drugs. * History of chronic headache and migraine. * History of cerebrovascular accidents and neurological disorders. * Systemic infection * History of uncontrolled DM or hepatic disease or pregnant female * Patient refusal or uncooperative patient.

What they're measuring

pain intensity of headache

Timeframe: From onset of the headache (0 hour).

pain intensity of headache

Timeframe: at 12 hours

pain intensity of headache

Timeframe: at 24 hours

pain intensity of headache

Timeframe: at 48 hours

pain intensity of headache

Timeframe: at 72 hours

Headache intensity

Timeframe: From onset of the headache (0 hour).

Headache intensity

Timeframe: at 12 hours

Headache intensity

Timeframe: at 24 hours

Headache intensity

Timeframe: at 48 hours

Trial details

NCT IDNCT04662125

SponsorZagazig University

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2023-08-30

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