Large-for-gestational-age (LGA) infants have a higher risk of metabolic disease later in life, and their postnatal growth in early childhood may be associated with long-term adverse outcomes. The purpose of this study is to explore whether comprehensive lifestyle intervention in the first year after birth in LGA infants will reduce the rate of overweight/obesity at childhood and improve neurodevelopmental outcomes and its possible mechanism.
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Rate of overweight/obesity at 2 years old
Timeframe: at 2 years old
Rate of overweight/obesity at 7 years old
Timeframe: at 7 years old