The Dose Effects of Isomaltulose and Sucrose on Glycaemic and Insulinemic Response (NCT04653207) | Clinical Trial Compass
CompletedNot Applicable
The Dose Effects of Isomaltulose and Sucrose on Glycaemic and Insulinemic Response
Singapore64 participantsStarted 2018-03-01
Plain-language summary
This study will determine the glycaemic and insulinaemic response and sensory profile of the drinks with various ratios sucrose:isomaltulose. The information will be useful for manufacturers of beverages to produce blood glucose friendlier drinks. The information will also be useful for dieticians and clinicians in recommending foods and drinks for people with diabetes. The information will also be useful to the public for making better food choices. The data will also provide insights on how the different ratios of sweeteners may affect glycaemic and insulinaemic indices (GI and II).
Who can participate
Age range
21 Years – 60 Years
Sex
MALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
* Males
* Asian selected from the three ethnicities Malay, Indian and Chinese
* Age between 21-60 years
* Do not partake in sports at the competitive and/or endurance levels
* Body mass index between 22 to 27 kg/m2
* Normal blood pressure (\<140/80 mmHg)
* Fasting blood glucose \<6 mmol/L
* Do not have an ongoing infection or currently undergoing treatment at the time of screening
* Do not have known Chronic infection or known to suffer from or have previously suffered from or is a carrier of Hepatitis B Virus (HBV), Hepatitis C Virus (HCV), Human Immunodeficiency Virus (HIV)
* Do not have active Tuberculosis (TB) or currently receiving treatment for TB
* Not on any concurrent research study/trials
* Do not smoke
* Do not have any metabolic diseases (such as diabetes, hypertension etc)
* Do not have glucose-6-phosphate dehydrogenase deficiency (G6PD deficiency)
* Not having medical conditions and/or taking medications known to affect glycaemia (glucocorticoids, thyroid hormones, thiazide diuretics)
* Do not have intolerances or allergies to foods including the test foods and fructose
* Do not partake in sports at the competitive and/or endurance levels
* Do not intentionally restrict food intake
* Do not have an ongoing infection or currently undergoing treatment at the time of screening
* Do not have known Chronic infection or known to suffer from or have previously suffered from or is a carrier of Hepatitis B Virus (HBV), Hepatitis C Virus (HCV), Human Immunodeficiency Viru…
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in postprandial blood glucose over 180 minutes period
Timeframe: 180 minutes
Trial details
NCT IDNCT04653207
SponsorSingapore Institute of Food and Biotechnology Innovation