United States185,903 participantsStarted 2020-12-02
Plain-language summary
Less than half of all positive fecal immunochemical testing (FIT)s are followed-up by colonoscopy, thus limiting the full potential of colorectal cancer (CRC) screening to reduce mortality. Given the need for coordination in order to achieve high rates of follow-up, multilevel approaches are needed. Such approaches could be particularly beneficial in communities and populations that experience cancer disparities and have fewer specialty providers, but most data focuses on large systems or urban areas. The academic-community health system collaboration is uniquely poised to address this research and service gap. The persistent poverty and health disparities in rural Southern Illinois set the stage for truly impactful research. The investigators' approach will serve as a model for multilevel interventions in rural settings, inform future work addressing other health disparities, and fill a gap in rigorous trials of CRC screening follow-up in rural areas.
Who can participate
Age range
45 Years – 75 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria for Primary Care Clinic Sites
* Physician Hospital Organization (PHO) affiliated with Southern Illinois Healthcare
Exclusion Criteria for Primary Care Clinic Sites
* Not a part of the PHO
Inclusion Criteria for Physicians and Staff at Primary Care Clinic Sites
* Employment at the relevant clinic at the time of the study
Exclusion Criteria for Physicians and Staff at Primary Care Clinic Sites
* Not employed at the relevant clinic at the time of the study
Inclusion Criteria for Patients
* Age 45-75 during the study period
* Must be patient of the selected primary care clinic sites
Exclusion Criteria for Patients
* Younger than 45 years of age or older than 75 years of age during the study period
* Not a patient of the selected primary care clinic sites
Inclusion Criteria for Community Members
* Age 45-75 at the time of the health fair or screening event
* Able to undergo stool testing as determined by SIH staff at the health fair or screening event
Exclusion Criteria for Community Members
* Younger than 45 years of age or older than 75 years of age
* Unable to undergo stool testing
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Number of Referrals for Colonoscopies After Positive Fecal Immunochemical Test
Timeframe: Within 60 days after receipt of positive FIT/FOBT
2
Number of Colonoscopy Completions After Positive Fecal Immunochemical Test (FIT)
Timeframe: Within 60 days of referral to Gastroenterology