COVID-19 Thrombosis Prevention Trials: Post-hospital Thromboprophylaxis

Inclusion Criteria: * • Age ≥ 18 years * PCR-positive COVID-19 infection * Hospitalized for two or more days Exclusion Criteria: * Pre-existing indication for anticoagulation (e.g., pulmonary embolism or deep vein thrombosis; atrial fibrillation; mechanical cardiac valve) * Contraindication to antithrombotic therapy (e.g., known bleeding within the last 30 days requiring emergency room presentation or hospitalization; major surgery within 14 days; ischemic stroke, intracranial bleed or neurosurgery within 3 months. * Platelet count \< 50,000/mcL * Hemoglobin \<8 gm/dL * Renal insufficiency (eGFR \< 30 mL/min/1.73 m2) * Pregnancy * Prison inmate * Life expectancy less than 90 days * Unwilling or unable to provide informed consent/unwilling or unable to complete the study protocol * Dual antiplatelet therapy that cannot be discontinued * Concomitant need for strong inducers/inhibitors of p-gp or CYP3A4