Active — Not RecruitingNot Applicable

Pain and Opioids: Integrated Treatment In Veterans

United States157 participantsStarted 2021-07-01

Plain-language summary

This trial will recruit veterans with chronic pain (N = 160) who are prescribed buprenorphine for the treatment of opioid use disorder (OUD). We seek to: (1) examine the efficacy of an integrated treatment to reduce pain interference (Acceptance and Commitment Therapy and Mindfulness-Based Relapse Prevention \[ACT + MBRP\]) compared to an education control (EC) consisting of a protocol-based series of education sessions concerning chronic pain, opioids, and buprenorphine use and (2) examine how theoretically-relevant treatment mechanisms of pain acceptance, engagement in values-based action, and opioid craving are related to treatment outcomes. Interventions will be delivered via the VA Video Connect telehealth modality.

Who can participate

Age range21 Years – 75 Years

SexALL

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Inclusion criteria

✓. Stabilized on a dose of buprenorphine for a period of at least 1 month and less than six months. Buprenorphine stabilization will be defined as a consistent dose for at least 30 consecutive days.
✓. Willing to comply with all study procedures and be available for the duration of the study
✓. Male or female, aged 21 to 75 years.
✓. Enrolled as a patient in one of the participating VA Co-Occurring Disorders clinics.
✓. Presence of chronic pain for \> 6 months in duration.

Exclusion criteria

✕. Current or past diagnosis of schizophrenia, delusional disorder, psychotic or dissociative disorders.
✕. Unable to read English.
✕. Have a substance use disorder requiring a higher level of care than outpatient treatment (e.g., severe alcohol use disorder requiring inpatient detoxification).

What they're measuring

Pain interference

Timeframe: Post-Treatment (month 3)

Trial details

NCT IDNCT04648228

SponsorUniversity of New Mexico

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-12-16

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