UnknownEarly Phase 1

Hemodynamic Stability of Dexmedetomidine in Hypertensive Patients Undergoing Laparoscopic Cholecystectomy

Pakistan44 participantsStarted 2020-12-30

Plain-language summary

Dexmedetomidine provides better hemodynamic stability to the patients with hypertension undergoing laparoscopic cholecystectomy.

Who can participate

Age range17 Years – 70 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Hypertensive patients of both genders of age 17 years to 70 years who are undergoing laparoscopic cholecystectomy. * ASA II and III Exclusion Criteria: * Patients with a prior history of cardiac disease like ischemic heart disease, valvular disorders, undergone previous valve replacements, infective endocarditis and rheumatic fever. * Renal diseases like acute kidney injury and chronic renal diseases. * Endocrinal diseases like pheochromocytoma, hyperthyroidism, hypothyroidism, cushing disease etc. * Pregnant and lactating females * Short thick neck with anticipated difficult intubation * Any sort of obstructive restrictive or reactive airway disease * Patient allergic to any of the study medications. * Obese patients (BMI\>35) * Narcotic addicts

What they're measuring

Change in Systolic blood pressure during pneumoperitoneum

Timeframe: From baseline to the end of pneumoperitonium, an average of 2 hours

change in Diastolic blood pressure during pneumoperitoneum

Timeframe: from baseline to the end of pneumoperitoneum, an average of 2 hours

change in Mean Arterial blood pressure during pneumoperitoneum

Timeframe: from baseline to the end of pneumoperitoneum, an average of 2 hours

change in Heart Rate during pneumoperitoneum

Timeframe: from baseline to the end of pneumoperitoneum, an average of 2 hours

Trial details

NCT IDNCT04646317

SponsorDr. Ruth K.M. Pfau Civil Hospital, Karachi

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2021-03-02

Contact for this trial

Muhammad Imran, FCPS

+923342947181 dr.imranriasat@gmail.com

View on ClinicalTrials.gov More Hypertension trials

Who can participate

Age range17 Years – 70 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Change in Systolic blood pressure during pneumoperitoneum

Timeframe: From baseline to the end of pneumoperitonium, an average of 2 hours

change in Diastolic blood pressure during pneumoperitoneum

Timeframe: from baseline to the end of pneumoperitoneum, an average of 2 hours

change in Mean Arterial blood pressure during pneumoperitoneum

Timeframe: from baseline to the end of pneumoperitoneum, an average of 2 hours

change in Heart Rate during pneumoperitoneum

Timeframe: from baseline to the end of pneumoperitoneum, an average of 2 hours