CompletedNot Applicable

Dermoscopy in Primary Raynaud's Phenomenon

France100 participantsStarted 2021-01-01

Plain-language summary

Raynaud's phenomenon (RP) is very frequent in general population (up to 10%). Nailfold capillaroscopy (NFC) is recommended for patients presenting RP, to eliminate systemic disease such as systemic sclerosis. NFC is not easily available in clinical practice. Dermoscopy, used for pigmentary skin lesion screening, may help to detect giant loops, hemorrhages or other capillaries anomalies. However, no study has evaluated the performance of dermoscopy in primary RP. The objective is to determinate which items in dermoscopy are correlated with a normal NFC and predict with a good negative predictive value, a normal NFC in RP patients. The secondary objective is to assess inter-observer reproducibility of dermoscopy in patients with RP.

Who can participate

Age range19 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * age \> 18 years * first consultation for bilateral Raynaud's phenomenon (RP) * Bilateral Raynaud's phenomenon affecting at least one finger of each hand defined by a paroxysmal syncopal phase on exposure to cold, * Affiliated to the French health care systeme Exclusion Criteria: * age \< 18 years * Presence of unilateral RP where the capillaroscopy is normal regardless of the cause

What they're measuring

Dermoscopic items

Timeframe: November 2022

Trial details

NCT IDNCT04644523

SponsorAssistance Publique - Hôpitaux de Paris

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2021-05-15

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